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ea0073oc11.5 | Oral Communications 11: Adrenal and Cardiovascular Endocrinoloyg | ECE2021

Results of the ADIUVO trial, the first randomized study on post-operative adjuvant mitotane in patients with adrenocortical carcinoma

Terzolo Massimo , Fassnacht Martin , Perotti Paola , Libè Rossella , Lacroix Andre , Kastelan Darko , R. Haak Harm , Arlt Wiebke , Loli Paola , Decoudier Benedicte , Lasolle Hélène , Bancos Irina , Quinkler Marcus , Barisson Villares Fragoso Maria Candida , Canu Letizia , Puglisi Soraya , Calabrese Anna , Kroiss Matthias , Dusek Tina , Bourdeau Isabelle , Baudin Eric , Berchialla Paola , Beuschlein Felix , Bertherat Jerome , Berruti Alfredo

BackgroundThe ESE-ENSAT guidelines suggest adjuvant mitotane for patients with adrenocortical carcinoma (ACC) at high risk of recurrence following radical surgery. This indication has a limited evidence base, lacking results from randomized controlled trials. No suggestion is available in low-risk patients, since studies did not stratify patients for prognosis. The randomized controlled study ADIUVO compared the efficacy of adjuvant mitotane (MIT) treatm...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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